That line running from your nose to the corners of your mouth — the nasolabial fold — is one of the earliest and most stubborn signs of facial aging.


You've probably noticed it getting deeper in photos, or maybe people have started asking if you're tired when you're not. And if you've been researching treatments, hyaluronic acid filler has likely come up as the go-to answer.

But there's a quietly growing approach in Korean dermatology that works completely differently — not by filling the line, but by rebuilding the skin around it.

Tansaeng Shot (Newborn Glow Shot), is one of them. Here's everything you need to know.

Why Do Nasolabial Folds Appear in the First Place?

Before choosing any treatment, it helps to understand what's actually driving the fold — because the root cause determines which approach will (and won't) work for you.

Collagen and elastin loss Starting in our mid-20s, the skin's collagen production gradually slows. As the structural proteins that keep skin firm and lifted diminish, the skin loses its ability to support itself — and nasolabial folds become more visible as that underlying support weakens.

Volume loss in the cheeks Age-related fat and bone resorption in the midface causes the cheeks to deflate and descend. This creates a height difference between the cheek and the mouth area — making the fold appear deeper even when the skin itself hasn't dramatically changed.

Skin laxity and sagging As the cheeks lose their lift, tissue migrates downward and accumulates at the nasolabial crease, forming a deeper, more shadowed groove. In these cases, skin quality treatments alone may not be enough — a lifting component is often needed alongside.

Understanding which of these factors is driving your nasolabial folds is the first step toward choosing the right treatment.

So What Exactly Is Tansaeng Shot?

Unlike hyaluronic acid fillers, which physically add volume to fill the fold from below, Tansaeng Shot works by reactivating your skin's own repair mechanisms — so that folds caused by collagen loss and skin quality decline gradually become less prominent over time.

Think of it as the difference between patching a crack in a wall versus reinforcing the wall itself.

Specifically, patients targeting nasolabial folds can expect:

  • Firmer, more elastic skin — as new collagen production rebuilds the skin's structural support
  • Improved skin texture and tone — reducing the visual contrast of the fold
  • Softened fine lines — as the skin regains density and hydration from within
  • A natural, healthy glow — that makes the overall complexion appear more youthful and rested

The gradual nature of these results means the improvement looks completely natural — never overdone or artificial.

Which Type of Tansaeng Shot Is Right for Your Nasolabial Folds?

At IRERAUM Clinic, we offer four formulations of Tansaeng Shot, each tailored to a different skin concern.

How to choose:

  • If skin laxity and collagen loss are the primary drivers → Skin formulation
  • If volume depletion in the midface is making folds appear deeper → Volume formulation
  • If you want enhanced skin regeneration on top of anti-aging results → Premium line (with Rejuran)

Our team will assess your skin individually at consultation before making a recommendation.

What Is Premium Tansaeng Shot?

Premium Tansaeng Shot is the advanced tier of the Tansaeng line, incorporating Rejuran (PDRN) — a skin regeneration ingredient well established in Korean dermatology for its ability to repair skin at a cellular level.

In addition to the collagen-stimulating benefits of standard Tansaeng Shot, the Premium formulation delivers:

  • Enhanced skin regeneration
  • Improved skin radiance and luminosity
  • Deeper repair of overall skin quality
  • More comprehensive anti-aging effects

It's a particularly good option if you want to address nasolabial folds while also upgrading your overall skin health — not just treating one isolated concern.

How Many Sessions Does It Take to See Results?

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Because Tansaeng Shot works by triggering your skin's own biological repair process, results build progressively. Here's what to expect across a standard course:

After Session 1 The skin begins its internal healing response. Most patients notice an initial improvement in skin quality and a subtle radiance boost.

After Sessions 2–3 Firmness and elasticity become noticeably improved. The skin feels more structured, and nasolabial folds begin to appear less defined.

3+ Sessions (Full Course) Collagen production is in full swing and structural benefits become most visible. Nasolabial folds caused by skin quality decline are noticeably softened, and the overall complexion looks refreshed and more youthful.

We recommend a starting course of 3 sessions spaced 4 weeks apart, followed by maintenance treatments every 6–12 months depending on your skin's needs.

What's the Downtime Like?

One advantage of Tansaeng Shot is the PDRN component's natural anti-inflammatory properties, which help suppress post-treatment redness and speed recovery compared to some other injectables.

Most patients can return to their normal routine the following day. Some mild redness, swelling, or occasional bruising is normal and typically resolves within 1–2 weeks.

If you have a special event coming up, we recommend scheduling your session at least 2 weeks in advance.

Is Tansaeng Shot the Right Treatment for Your Nasolabial Folds?

Tansaeng Shot works best for nasolabial folds caused by:

  • Collagen loss and reduced skin elasticity
  • Early to moderate skin laxity
  • Midface volume depletion (Volume formulation)
  • General decline in skin quality and texture

For more pronounced folds driven by significant sagging or deep structural changes, Tansaeng Shot may work best in combination with hyaluronic acid fillers or lifting procedures. Your provider will guide you after a thorough assessment.

FAQ — Tansaeng Shot for Nasolabial Folds

Q. Can Tansaeng Shot alone improve my nasolabial folds?

A. For folds caused primarily by collagen loss and reduced skin firmness, yes — Tansaeng Shot can produce meaningful improvement. For deeper folds driven by significant volume loss or sagging, a combination approach may be recommended.

Q. How is Tansaeng Shot different from hyaluronic acid filler?

A. Hyaluronic acid filler physically adds volume to fill the fold from below. Tansaeng Shot works differently — it stimulates your skin's own collagen production to gradually rebuild its internal structure, reducing the appearance of folds naturally over time.

Q. Which formulation is best for nasolabial folds?

A. It depends on what's driving the fold. Skin-type formulations address collagen and texture decline; Volume-type formulations target midface volume loss. A consultation will help determine the right fit for your specific concern.

Q. How soon will I see results?

A. Initial changes in skin quality and firmness typically become noticeable 2–4 weeks after the first session. Nasolabial fold improvement is usually most visible after completing a full course of 3 sessions.

Q. What's the difference between Tansaeng Shot and Premium Tansaeng Shot?

A. The Premium formulation includes Rejuran, which adds enhanced skin regeneration and radiance effects on top of the collagen-stimulating benefits of the standard treatment.

The Bottom Line

Nasolabial folds don't have to mean fillers — especially when the underlying cause is collagen loss and declining skin quality.

Tansaeng Shot offers a biologically grounded approach to this concern, working with your skin's own repair systems to rebuild the structure that makes folds less visible. The results are gradual, natural-looking, and cumulative — and for many patients, the improvement extends well beyond the fold itself, into an overall skin quality that simply looks and feels healthier.



If you're curious whether Tansaeng Shot is the right fit for your skin, we'd love to help you find out.

Book a consultation at IRERAUM Clinic Gangnam today.